CFIm: The Protein Linked To Cell Division and Cancer (P22505)

Target Name: Cleavage factor Im complex

NCBI ID: P22505

Cleavage factor Im complex

Other Name(s): CFIm

CFIm: The Protein Linked To Cell Division and Cancer

Cleavage factor Im complex (CFIm) is a protein that plays a crucial role in the regulation of cell division and has been linked to various diseases, including cancer.CFIm is a protein that is composed of four subunits: alpha, beta, gamma, and delta. It is expressed in a variety of tissues, including the brain, pancreas, and gastrointestinal tract, and is involved in the regulation of cell division, differentiation, and survival.

One of the most significant functions of CFIm is its role in the regulation of cell division. CFIm is involved in the formation of the mitotic spindle, which is the structure that pulls the chromosomes apart during cell division. It is also involved in the regulation of the actin-associated protein (APC) complex, which is responsible for the stability of the mitotic spindle.

In addition to its role in cell division, CFIm is also involved in the regulation of cell survival. It has been shown to play a role in the regulation of cell apoptosis, which is the process by which cells die naturally in response to various stimuli, including exposure to chemotherapy drugs.

CFIm has also been linked to the development and progression of certain diseases, including cancer. For example, studies have shown that high levels of CFIm are associated with poor prognosis in patients with pancreatic cancer, and that inhibition of CFIm has been shown to improve survival in these patients.

Despite these promising findings, much more research is needed about CFIm and its role in disease. One of the main challenges in studying CFIm is its complex structure, as it is composed of four subunits that are difficult to study individually. In addition, the functions of CFIm are not well understood, and it is not clear how they are involved in the regulation of cell division and survival.

In conclusion, CFIm is a protein that is involved in the regulation of cell division and survival. It is expressed in a variety of tissues and has been linked to the development and progression of certain diseases, including cancer. Further research is needed to fully understand its role in these processes and to develop new treatments for these diseases.

Protein Name: Cleavage Factor Im Complex

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